Navas then had to keep out a strike from Koke as the visitors looked to complete the turnaround at the Bernabeu.
In the 90th minute Madrid were awarded a free-kick on the edge of the box but Oblak tipped Sergio Ramos effort over the bar for a corner.
One point apiece was fair for two teams whose focus is on Europa competition.
Zidane, with one eye on the Champions League quarter-final second leg against Juventus on Wednesday, started with Luka Modric and Karim Benzema on the bench, the latter coming on to spare Ronaldo the final half an hour.
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He added: "I think when teams are able to make short passes of four or five metres, you lose the risk to lose the ball". Mourinho let De Bruyne leave Chelsea in January 2014 - and Mohamed Salah , now starring at Liverpool , a year later.
"We have been training hard, preparing for this weekend's game".
The 24-year-old has made 27 appearances in the league this season, fashioning three goals.
Nevertheless, the former Real Sociedad player has scored a league goal vs. Madrid in each of the last six seasons and on his last three visits to the Bernabeu.
Although captain Sergio Ramos twice went close in stoppage time, Madrid were unable to force a victor and remain third - four points behind their neighbours in LaLiga.