He was referring to al-Tanf region in southern Homs province, where the Pentagon has a military base.
"Don't believe anything that is said about an agreement on the south until you see that the United States has withdrawn its forces from the At-Tanaf base", he said. He said Israel and Russian Federation were holding intense discussions regarding Iranian military presence in Syria, which he believes is spearheaded at Israel.
On Friday, the newspaper reported Israel and Russian Federation had reached an agreement green-lighting Israeli strikes on Iranian targets in Syria, as well as the withdrawal of Tehran-backed troops from Syria's border with Israel.
"The U.S. presence in Syria is illegitimate and they should withdraw from al-Tanf and any other area in Syria", he noted.
Syrian government forces, in their strongest position since the early months of the seven-year conflict, have driven rebels out of all territory near the capital Damascus this year.
Elsewhere, Shamkhani said that Iran considers Syria's security as its own and that "stability in Syria is an achievement for Iran".
Jazayeri, who is an adviser to Iranian chief of staff, told Tasnim that the biggest fear of the "Zionist regime of Israel" was having Muslim fighters in the region, and that Israel and the USA were desperate to change the situation.
The US's presence in Syria is not sanctioned under worldwide law.
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"The second thing", Netanyahu went on to say, "is the blocking of Iran's plans for expansion and aggression throughout the Middle East, especially in Syria".
The Kremlin said President Vladimir Putin spoke with Prime Minister Benjamin Netanyahu Thursday evening to discuss the situation in Syria.
Russian Ambassador Vasily Nebenzya announced to journalists Friday that an agreement was reached that would involve removing all Iranian forces from the Syria-Israel border in the Golan Heights.
Over the years, Israel has watched as different groups in southern Syria came to control different parts of the area near the Golan border.
The agreement appears to be slated to demand that Iranian and Iran-backed forces stay 20 kilometers from the Israeli and Jordanian borders.
Iran has no military advisers in southern Syria, a senior Iranian security official was quoted as saying on Saturday, adding that Tehran supports Russian efforts to bring the area under Syrian army control.
Al-Muallem added at a press conference, "we sent 50 names, the Syrian state should have the majority in any number which will be agreed upon, and the committee's decisions should be taken unanimously".
In an interview with Russia's RT television network on Thursday, Syria's President Bashar al-Assad said the United States "is losing its cards" as the militant groups it supports have lost significant ground on the battlefield against the army, emphasizing that the Americans "should leave" Syrian soil.