Speaking after releasing the squad, Southgate said: "I am still able to look to the future in terms of the squad we have picked".
Goalkeeper Peter Shilton, who with 125 caps is the only player to have represented England more times than Rooney, and ex-captain Alan Shearer both agreed that Rooney's achievements deserve honouring - but that should not extend to him playing in the match.
"Callum is a striker we worked with briefly with the Under-21s so we know plenty about him", Southgate said.
"We talk to them a lot about that they have the shirt now but it is not their shirt, great players have worn it before them and great players will wear it after them", Southgate added.
Rooney was one of 28 players selected Thursday (NZT Friday) by Southgate, but the former captain will not play on November 18 against Croatia in England's final Uefa Nations League game.
The return of record goalscorer Rooney has split opinion, with the 33-year-old set to collect a 120th cap in the November 15 friendly against the U.S. to honour his Three Lions career.
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A key topic on the agenda was the prospect of a partisan home crowd and the influence Red Star's supporters can have on both teams.
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Then, finally, after years of waiting, Triumph finally came face-to-face with Cruz at a Republican rally. Meanwhile, a comedy bit put the candidates in the national spotlight yet again.
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The Russian fully demonstrated his confidence later on, finishing quadruple breaks for a 6-1 second set victory. Khachanov continued to press on for his second break in the 11th game and served out the opening set at 7-5.
The 33-year-old Rooney, now playing in Major League Soccer with DC United, has not played for England in nearly two years.
"It's a real good thing for everyone to be a part of".
"I understand people have got different opinions but, from knowing Wayne and what he's done for England, I don't see any problem with it".
"I've not spoken to Gareth (Southgate) too much about how he's going to do it when we play but it'll be great to see him again and I'm sure he's looking forward to seeing a few of the boys".
"If we're also talking about helping young players develop in the worldwide set-up, then surely celebrating Wayne's career in this way is an example to the next generation of England stars". I think he's earned the right to that cap over a period of over 10 years, six major tournaments and being our record goalscorer.
Kane has scored 19 times so far in his England career - 34 goals shy of Rooney's current record of 53, but was non-committal on whether he has an eye on surpassing that tally. If I had been a player, and had given what those guys had given, I'd have walked away from there feeling my association have really recognised me in a fitting way.