Three Vietnamese tourists and an Egyptian guide were killed and at least 10 others injured when a roadside bomb blast hit their tour bus on Friday less than 4 kilometers from Egypt's world-famous Giza pyramids, authorities said.
Security forces rushed to the scene in response and police are investigating.
At least 10 other Vietnamese tourists, as well as an Egyptian bus driver, were also hurt in the blast, the interior ministry said.
"It was awful - people screaming", she said.
The bus was carrying a total of 14 Vietnamese tourists, it added, saying only two of them escaped unharmed. "I don't remember anything after".
No group took immediate responsibility for the incident.
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The white tourist bus could be seen with its windows shattered and surrounded by soot-covered debris.
The injured were taken to the nearby Al Haram hospital, where Mr Madbouly told local media the tour guide had died from his injuries.
Prime Minister Madbouly told reporters that all tourstim trips and their routes are highly secured in a detailed manner by the interior ministry.
Egypt has battled Islamic militants for years in the Sinai Peninsula in an insurgency that has occasionally spilled over to the mainland, hitting minority Christians or tourists.
The country has been under a state of emergency since April 2017, following a series of terrorist attacks against Coptic Christian churches in the Nile delta.
Friday's attack however is the first attack to target foreign tourists in nearly two years. "We will proceed together towards another year of persistence in uprooting terrorism", Hafez wrote on Twitter.